All of this information, advice, and insights are incredibly helpful. Thank you all so much. We met with the surgeon yesterday and he is recommending 4 months of chemo prior to surgery to both address the margins (her tumor is getting close to some major vessels) and kill off any cancer cells floating around in her body. She’s still hopeful, but without knowing how she’ll react to the chemo - especially at first when they’re guessing how much and the frequency - she’s overwhelmed by a desire to “just be normal again.” For now, the Whipple is still on the table and as long as the chemo does its job, looking like that it will be her decision to opt for the open surgery.