← Return to Kevzara and Prednisone Tapering before and during Kevzara

Discussion
Comment receiving replies
Profile picture for khof @khof

I'm wondering about tapering off prednisone when I'm on Kevzara. I've been on Kevzara for 5 months and have tapered prednisone from 12 mg to 3.5 in that time. Just got back from rheum and he want me to go to 1 mg next week and be off prednisone in 2 weeks. Based on what I've read on this site, your adrenal glands need a little time to kick in. I asked him about it (especially since it looks like so many people on this site needed to see and endocrinologist at around 3 mg. due to adrenal glads) and he said since I'm on Kevzara I should be fine and if I'm having problems go up to 5 mg. Just wanted to sound out the group. I might just be scared to reduce so quick because the two flares I had were pretty bad. I really want to get off prenisone, but not play "Cutes and Ladders".

Jump to this post


Replies to "I'm wondering about tapering off prednisone when I'm on Kevzara. I've been on Kevzara for 5..."

That sounds risky to me. The Kevzara should prevent a flare of your PMR, but you could have adrenal issues by dropping from 3.5 mg down to 0 in just 3 weeks or so. I take Actemra, which is very similar to Kevzara, and my rheumatologist had me taper 1 mg every 4 weeks once I got to 5 mg. That worked very well for me. By the time I got down to 2 mg I felt like the prednisone wasn't causing any side effects.

I like to think of it like a plane landing. Do you want your plane to glide in low and slow on a long flight path, or do you want it to stop suddenly and drop to the ground from several thousand feet up?

I had a similar experience with my Rehum, except he wanted me to go from 8mg to “0”.
Not me……..I self tapered with my PCP approval.
I am at 5 months Kev now. I started my taper at 8mg, was at 3 mg by 6/15 (16 wks on Kev). I did self taper to “0” by 7/13. I did it in .5 increments.
I was having no symptoms, exercising more.
I 🛑 prednisone on 7/13.
Note: I do supplement with 2 Tylenol for Arthritis when weather is hot/humid (today total 165%) or I have overdone it. I traveled to Alaska recently and needed no supplements.

As everyone on this blog says, you do what you “feel” works for you. Good luck

Diagnosed with PMR in 2011. . Because of a flare in late fall of 24 my rheumatologist raised my prednisone. When I got to 10mg I started KEVZARA. I held at 10mg for a few weeks then tapered 1mg/week. to 3and held for a while then dropped to 0. That was the first of June. I had also had a morning cortisol test at 3mg and I was in the normal range. After the test is when the rho rheumatologist told me to continue with the taper.
So if concerned about adrenal issues ask for a morning cortisol test.