I try to stay up-to-date on my health readings, including supplements. In fact, I found some helpful information a few months ago that caused me to curtail certain supplements during my SBRT radiation treatments. I think it's highly advisable to question and evaluate whether certain supplements might be problematic for prostate cancer purposes.

Speaking for myself, I've found certain AI programs to be quite helpful in assisting my prostate cancer researching. In particular, I have been very pleased with the relatively low subscription cost "Perplexity.AI Pro" program. This AI program provides analysis and reports which include direct links to supporting evidence-based information sources.

So...what does this AI say about whether creatine supplementation increases prostate cancer risks? According to the attached report - which includes the consideration of 37 separate scientific resources - the conclusion suggests the answer is "no".

Here's the opening paragraph of this report:

"No Evidence of Increased Prostate Cancer Risk from Creatine Supplementation
Current scientific evidence does not support claims that creatine monohydrate supplementation increases prostate cancer risk in men. In fact, the research suggests either neutral effects or potential protective benefits."

I did a little research:
In men on ADT, a controlled trial found creatine did not improve strength/muscle gains beyond training, but also showed no harm or disease progression signal.
Large ongoing trials (like CREATINE-52) are directly testing whether creatine affects cancer progression in men with advanced prostate cancer. Results are pending.
Population data even suggest higher dietary creatine intake is linked to lower odds of cancer overall (observational, not proof).
Lab studies are mixed, but some show creatine may support immune responses against tumors rather than feed them.
For men on ADT:
Creatine may give a modest brain boost, and current human data show no evidence that it promotes prostate cancer progression. Ongoing trials will give us clearer answers, but right now it looks like a safe option for most men on prostate cancer treatment.