Years ago, when I fosamax, it did raise my blood pressure. I would schedule all my annual visits to my various doctors in the summer. First ob/gyn. In the 140s. I thought it was just a blip. Then a few weeks later at my endocrinologist. Same. Then a few weeks with the gastroenterologist. 140s again. So I discussed it with my PCP and he had me come in every 2 weeks just to check my blood pressure. It was consistently high for 6 weeks. He advised me to stop taking it (he wasn't the prescribing doctor) and at my next 2 week follow up I was down to my normal 120/60. When I brought this up to my prescribing doctor (endocrinologist) he said he had never heard of that as a side effect. Well, remember that was back in the day when doctors mainly got their drug information from drug reps who catered to them with lunches and gifts. (Has since been outlawed) Probably drug reps are still the doctors' main source of information on drugs. At any rate, I went on a research binge and found a Canadian study buried deep in the Google woods that stated that the #1 side effect of fosamax was esophageal irritation, and #2 was high blood pressure.