Well, icorps, it certainly seems like a study worth doing; overtreatment is nobody’s idea of fun, right? And of course, thank you for your service to our cause!
In another discussion (last week maybe?) it was mentioned that before PSMA, bone scans were the gold standard for retreatment; if it’s not in the bones you’re OK. We can all see the shortcomings in that line of reasoning, but it mostly worked…
I’ve long felt that PSA doubling time/velocity is the real measure of aggressiveness and I hope the study - of which you are a part - validates this beyond a doubt.
But I can think of the men with very aggressive cancers whose cells do not produce much PSA really throwing a wrench into the hypothesis.
What do you tell a patient who has multiple metastases to the ribcage discovered on a chest Xray during a yearly physical? Yikes! Again, so many damned exceptions…Best,
Phil