I have had five injections so far. Depending on the person that gives a shot, sometimes it hurts a little afterward, but supposedly if they warm up the shot, it hurts less. as far as I can see I’ve had no side effects. I have had multiple compression fractures and a serious femur fracture. At this point, I was willing to try anything as my bone density is so poor. Hopefully after the regimen I will have obtain some new bone growth. I have been taking Prolia up to now, but that doesn’t seem to have decreased my bone loss.