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Can Prostate Cancer "Take a New Trajectory"?
Prostate Cancer | Last Active: Aug 29 6:50am | Replies (46)Comment receiving replies
Ok. I'm the original starter of this thread. Let me follow-up--
After prostatectomy + radiation + ADT (orgovyx), I've been PSA < 0.01 for little over 2 years.
At my Drs recommendation, I came off ADT mid-July. I've got my first labs coming up mid September.
If PSA starts to rise, this is called a biochemical recurrence (BCR)? At what point do we start thinking that cancer has reoccurred? When is a followup PET scan done?
So, I've been < 0.01. When it's determined that I need to get back on treatments?
My cancer was stage 4a, Gleason 9, Decipher .99. So, from the start my Drs have always said the cancer is aggressive and we are going to be aggressive in treatment. So, I'm completely dumbfounded what's to be gained by taking me off ADT! It just seems to be taking a risk that is completely unnecessary!
My PSA has been < 0.01--- why screw this up?
I forgot to mention, a PSMA scan a while back (over a year ago) picked up a small lung nodule. I've had 2 followup CT scans since and the nodule has not increased in size. I'm now kinda worried that with me going off ADT, if it's metastatic cancer that it may start to grow!!
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Very interesting study - my hub would have been a good candidate except his PSA never got to 0.5 - his lung only Mets was discovered with PSA 0.36 - we pondered doing treatment as it had been 17 yrs since RARP and he had no symptoms. He had lost weight but had been playing with a keto diet….Anyway, of two expert docs, one suspected aggressive cancer type, the other (we met after tax started) suggested it was an indolent form. Just finished chemo with docetaxel + carboplatin - follow-up PSMA PET coming up in 2 weeks. Will we ever know what might have happened had we not treated the first time or second? No, so that’s the game. Hub and 4/10 brothers diagnosed including hub; one did seeds and no recurrence, 2 others had surgery and no recurrence. Oh, and a genetic link is yet to be discovered. So again, this disease is incredibly nuanced. It seems beneficial that the approach gets more personalized.