I had 12 rounds of folfirinox followed up by radiation and my neuropathy got pretty bad, especially in my feet. My oncologist recommended no supplementation until I had completed all treatment. Shortly after completion a year and a half ago I started a variety of supplementation to help me regain my health but it wasn’t until about two months ago I decided to target the neuropathy. I’ve been taking ALA and NAC daily. I’m not sure how well it is working but my neuropathy is less bothersome. I’ve had less cramping in my toes and more mobility. Still have the tingly sensation. The other side effect is that my energy level shot through the roof. I think it has to due with the beneficial effects these two supplements synergistically have on glutathione production.