It was scary for me, as well, when I started the big 3. I started the first on August 1, added the 2nd on August 4 and the third on Aug 8. At this point I haven't been told/asked to do the IV drugs. I haven't experienced any nausea which is great. I'm so pleased with that. After adding drug #2, I had with a low-grade fever off and on for several days but it has mostly subsided. I still wake up at night in a sweat but I can get back to sleep after not too much time. I'm taking probiotics and really focusing on eating well as I don't want to lose weight. My energy is not as good as it once was but its not bad and I am going to the gym on a regular basis. Still, I'm fearful as they're monitoring my blood, my heart etc. It's intimidating but I'm getting support from friends. One day at a time is how I'm tackling it. I hope it goes well for you ... and for me.