← Return to Reclast: Poor Result...Next steps

Discussion
undetectable avatar

Reclast: Poor Result...Next steps

Osteoporosis & Bone Health | Last Active: Sep 26, 2025 | Replies (35)

Comment receiving replies
Profile picture for pauladiamante @pauladiamante

Actually, Having been to medical school I am very certain that I know the difference between osteoclasts and Osteoblasts. Just sayin'.... Don't believe everything you read.... You are invited to check my facts.
I am doing my research on Medications, since I am not an endocrinologist and this discussion site has really helped direct my reading and learning. Iam very grateful for that.
For Example, Look up the mechanism of action of Fosomax, it will increase the new bone formation (Increasing the P1NP) AND decrease the bone breakdown (lowering the CTX) and both those numbers can be followed for titration of medication. PRETTY COOL!!!

Jump to this post


Replies to "Actually, Having been to medical school I am very certain that I know the difference between..."

I’m familiar with the mechanisms of action for osteoporosis drugs and with how markers like CTX and P1NP (which can be nuanced) are used in monitoring, which is why your earlier comment caught my attention. I’d really appreciate a reference for the product you mentioned that both builds bone and slows breakdown - I’d love to read more about it. Would it be Evenity you’re referring to, which was approved back in 2019? And to be clear, I have no doubt about your understanding - nor about gently’s, given how closely she’s tracked her own markers for quite some time.