I would strongly advise you to get the shingles shot before you start Kevzara. According to my rheumatologist—a Biologic plus Prednisone increases your risks for contracting shingles. I had my shingles vaccine several years before PMR but still came down with shingles 6 months after starting Actemra. My shingles were contained to one area and did not blister (which my doctor believes is because of the previous vaccination) but I still got them. Unfortunately the combo of Biologics and Prednisone really depletes the immune system and I had to completely stop taking the Biologic while I had the shingles. Apparently, your body doesn’t know how to heal from it if you continue taking the Biologic. For me that meant that the PMR & shingles pain were both significant. I did take Voltran to help with the shingles and it did help but I would advise doing EVERYTHING you can to avoid it. Good luck to you and hopefully Kevzara will be very beneficial. Blessings! ❤️