I, too, feel my grandmother had PMR, but prednisone just wasn't available for her. She walked with a horrible limp and could barely move her arms due to shoulder pain. So, genetics? Yes, I believe there's some predestination.

I'm a runner of 52 years and have wondered if environment/past inspired this nasty disease. I am also a DES baby (my mother took Diethylstilbestrol while pregnant with me 68 years ago which can cause, among a myriad of other side effects, autoimmune diesase.) I have always been a high-energy, nervous, stressed-out person.

I searched for a study regarding this to partake in as I live in the Raleigh area where a ton of universities are located. Couldn't get in.

I'm am now on an anti-inflammatory diet and still exercising. Reducing prednisone (now at 6.5 mg) is tough. I've had pain, fatigue, insomnia, depression, and bouts of anger!!! (I've pretty much given up everything I love. Just don't hint about giving up coffee. I mean it. I'll go beserk!!!!! It's my last vice---well, not according to my husband and kids, but really it is.)

My biggest challenge? No one understands. People look at me like, you have arthritis, so what?

Ugh, some golden years.