I'm not a doctor, but I really think you should do everything you can to try Enhertu (I recall that you're HER2+, correct?). If your doctor can't get you on it, you should try a different doctor. If you are in the US, you are absolutely eligible for it now, having failed platinum based chemotherapy.

IMO it's crazy for them to keep you on Keytruda. If it didn't work together with carbo/taxol, it's not going to work alone. It's things like this that make me wonder if doctors have a financial incentive to order Keytruda, which makes huge amounts of money for Merck per dose.

There have been some not-so-happy campers on Enhertu on this forum lately, but other people have had pretty good experiences. It would be a shame not to try it.