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Switch from letrozole to exemestane

Breast Cancer | Last Active: Nov 9 2:17pm | Replies (46)

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Profile picture for llthomson @llthomson

So sorry that you are going through this. I am also taking a month off before starting exemestane. I have been on anastrozole for 1 year and 7 months. Joint pain was continuing and oncologist did not want it to affect my right hand more and my ability to exercise. However, what you are describing is worse. Have you consider anastrozole brand name? I read that some feel much less side effects from the name brand (Arimidex). I am thinking I may asked to do that if exemestane does not work for me...

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Replies to "So sorry that you are going through this. I am also taking a month off before..."

Cost is sometimes a factor as well. I had read about some people using only brand name and not generics and doing well so I looked into it. Not covered by my insurance so I would pay out of pocket. Cost for brand name arimidex is 3-400.00/month and for aromasin is over 1300.00/month. So generic it is. I can handle the 70.00. I have read about the every other day dosing and may consider that. The half life is 24 hours. So every day means you are staying pretty much at full dose (take the next pill when 1/2 of first one is gone), every other day means you are kind of pyramiding it (take the next dose when the first one is completely gone. So zero start, to 1/2 dose at 24 hours, back to zero at 48 hours then next pill). Will do more research but definitely in my question list for next visit.
I just want to say I appreciate the responses. Just to know we’re not in this alone and NOT CRAZY. Friends and family either don’t want to talk about this or feel like since primary treatment is done, you should be back to feeling normal. They don’t understand that I still have side effects from the chemo and radiation even at 18mo (and maybe for years). The doctors often either don’t admit or don’t understand that what we are feeling now may be due to this medication even if it’s not a typical side effect. So thank you for everyone on this site for your help and input. Hopefully I am contributing helpful information as well.