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Agree, we need more studies on the impact of inhaled saline NTMs. Does anyone know how many years the BE/NTM clinics have been pushing saline inhalation for BE and NTM? I've been told and have read that spontaneous culture conversion occurs in 10-15% of people with BE and NTM. The few studies I have seen on inhaled saline as a treatment showed a much higher rate of culture conversion. Also, how long is recommended to nebulize 2/day after culture conversion. Though I will always nebulize with BE for prevention, it would be interesting to see how many months or range of months to get one from culture conversion to cured (of the original infection). The Portland/NYU Langone study on inhaled saline treatment for those with NTMs, will hopefully start soon.

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Replies to "Agree, we need more studies on the impact of inhaled saline NTMs. Does anyone know how..."

I haven't had positive MAC cultures, but do daily albuterol neb and airway clearance for bronchiectasis and mild asthma.

I had repeated viral infections 2 winters ago (young grandchildren) and last fall my pulmonologist suggested I try 7% saline a few times/week to see if that would help prevent them. I did it and haven't had any since November. Coincidence or cause? I don't know, but docs are using hypertonic saline even with negative sputum.

@kathyjjb what studies are you referring to re the rate of culture conversion with the use of saline and NTM? I have only seen one study specific to saline and NTM and the culture conversion rate was (off the top of my head) 12% which is consistent with the known data on spontaneous conversion. Interested in reading any other studies out there on saline and NTM. Thanks.