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@bronchiectasaurus I think you ask good questions. There is still a lot unknown about inhaled saline and airway clearance. I think someone just posted on an ongoing study being done on the impacts of inhaled saline on NTM infections. We definitely need more data. There are many different opinions and everyone seems to be guessing. As a result, for now, there seems no real basis for any hard and fast rules. I encourage you to experiment and find what works best for you.

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Replies to "@bronchiectasaurus I think you ask good questions. There is still a lot unknown about inhaled saline..."

Agree, we need more studies on the impact of inhaled saline NTMs. Does anyone know how many years the BE/NTM clinics have been pushing saline inhalation for BE and NTM? I've been told and have read that spontaneous culture conversion occurs in 10-15% of people with BE and NTM. The few studies I have seen on inhaled saline as a treatment showed a much higher rate of culture conversion. Also, how long is recommended to nebulize 2/day after culture conversion. Though I will always nebulize with BE for prevention, it would be interesting to see how many months or range of months to get one from culture conversion to cured (of the original infection). The Portland/NYU Langone study on inhaled saline treatment for those with NTMs, will hopefully start soon.