Can I ask, which type of chemo were you on?
My mum has pancreatic ductal adenocarcinoma, initially diagnosed stage 3 borderline resectable, was put on gemcitabine/abraxane initially but the tumour grew, then switched to modified Folfirinox with dose reduction due to age, after 3 cycles, repeat scans showed new liver lesion 1cm and the activity index of the primary tumour has increased. We are now looking to arrange another biopsy to hopefully fine a genetic mutation so that she will be eligible for some sort of immunotherapy. The oncology team did suggest to switch her to Onivyde+5FU but I am not sure for someone who did not respond to Gem/Abrax and Folfirinox, whether there will be response to Onivyde+5FU. Would be grateful for any responses.