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Hi Jeff,
All at UCSF..remeber mine was not a regular biopsy, it was after my Holep IPC but here are the result

FINAL PATHOLOGIC DIAGNOSIS Prostate gland, holmium laser enucleation: Prostatic adenocarcinoma, Gleason score 3+4=7; COMMENT: Gleason score 3+4=7 prostatic adenocarcinoma, with approximately 5% Gleason pattern 4, is present, and involves approximately 20% of tissue. The types of Gleason pattern 4 present include the fused glands and poorly formed glands type

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Replies to "Hi Jeff, All at UCSF..remeber mine was not a regular biopsy, it was after my Holep..."

So they found cribriform glands too ?
If yes, than I am also really confused with a proposed plan : (.

Honestly, ECE, even if it’s barely visible, is telling you bluntly that cancer cells have reached, and possibly breached the confines of the gland. This is serious…
You only need a few cells to travel snd take up residence elsewhere, taking you to the level of metastatic disease. How an RO could dismiss this finding - and then tell you that you have TEN years to worry about it, is very concerning.
Not sure which RO is telling you about the hole caused by HOLEP and its possible implications for Cyberknife, but even if that caution is valid it doesn’t mean that you should dismiss treatment for ECE.
What about IMRT?
Unfortunately, you need a third opinion…but a repeat biopsy targeting the ECE could be nasty as well; do you want 12 or more jabs into an area which is already bordering on breaking out of the capsule?
We’ve often debated here about biopsies ‘seeding’ the body with PCa cells, and although it’s mostly been debunked, I personally would have reservations about poking around a very iffy area.
Phil