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Profile picture for jeff Marchi @jeffmarc

You had a 3+4 Gleason. One main question is what percentage of that 3+4 had cancer and what percentage of it was a 4?

If they are very low percentages, then active surveillance makes sense if they’re high percentages then it doesn’t make sense.

If they didn’t tell you what the percentages are then ask them.

Extracapsular extension (ECE) in prostate cancer refers to the tumor's growth beyond the prostate gland's outer capsule. It's a sign of locally advanced disease and is associated with a worse outcome. I would want the doctor to explain why this isn’t a major issue.

Are you in Canada? Where are you being treated? This sounds like a case where you really need a second opinion from a center of excellence.

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Replies to "You had a 3+4 Gleason. One main question is what percentage of that 3+4 had cancer..."

Hi Jeff,
All at UCSF..remeber mine was not a regular biopsy, it was after my Holep IPC but here are the result

FINAL PATHOLOGIC DIAGNOSIS Prostate gland, holmium laser enucleation: Prostatic adenocarcinoma, Gleason score 3+4=7; COMMENT: Gleason score 3+4=7 prostatic adenocarcinoma, with approximately 5% Gleason pattern 4, is present, and involves approximately 20% of tissue. The types of Gleason pattern 4 present include the fused glands and poorly formed glands type

Mauk mentioned UCSF.