@mnewland99 I started the trial Wednesday. It was a very long day; left home at 6 AM and not back home until 7:30 PM. The pharmakokinetic testing (EKG's and blood draws) was spread out over 8 hrs. I felt pretty good during the 2 hr. Cetuximab infusion but things weren't great after that. Was achy and a bit chilled when I got home, went straight to bed, but didn't really sleep at all because of the aches and temp swings. Took my temp every couple hours and it was always a little high but never more than 100.3. Yesterday I had to pretty much lie low; digestion and bowels were off, and no appetite mostly from mild nausea. It's the same kind of nausea I have had for over a week since I started taking prophylactic Doxycycline. Called my doctor and she didn't seem too concerned. Appetite was a bit better last night and I slept fine and was feeling decent this morning. Went for an easy hour bike ride around 10 AM, came home to have some lunch and now I feel like I've taken a few steps back so back to the couch for the afternoon. Appetite gone, nausea, etc.

The irony of all this is the last 48 hours I have had more negative side effects from this than from 22 rounds of Folfirinox. Hopefully things will straighten out
soon. I go back next Wednesday but just for more monitoring/testing, then the following Wed I go back for testing and Cetixumab (that is every two weeks).