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In praise of Orgovyx

Prostate Cancer | Last Active: Dec 20, 2025 | Replies (81)

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Profile picture for jeff Marchi @jeffmarc

I take Diltiazem, Losartan and Metoprolol twice a day for high blood pressure (Due to Zytiga). All my blood tests are normal and really don’t change from month to month. Been on them for over 4 years.

I guess the right drugs make a difference. The question is what are the right drugs, it must vary depending on a person’s medical makeup.

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Replies to "I take Diltiazem, Losartan and Metoprolol twice a day for high blood pressure (Due to Zytiga)...."

Hey Jeff, Losartan really hit my gfr - lowered it more than 30 pts in less than a year and was trending lower when I stopped it.
Good that it hasn’t affected you; my friend is almost on dialysis because of it.

Phil, Jeff, others. Just saw this after getting my bloodwork done in prep for PT.
I’ve been on Orgovyx since Jan 25. No significant SEs compared to what I hear on the forum. But checking my BP it was very high again. I didn’t think about the ADT causing that rise.