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Do Pluvicto patients live like those in the TV ad
Prostate Cancer | Last Active: Aug 26 10:30am | Replies (30)Comment receiving replies
I recently attended a Q&A session with urologists about prostate cancer, and one radiologist was praising the merits of Pluvicto as the best thing when hormones fail, and side-stepping my question about side effects. Are any of you fellows out there that are on Pluvicto having an easy time of it with few or no side effects? This would be important feedback for the next session I attend in person.
Replies to "I recently attended a Q&A session with urologists about prostate cancer, and one radiologist was praising..."
I've been through 3 treatments with #4 coming up next week. Side effects are difficult if not impossible to nail on Pluvicto. Within the week after all the injections I've had effects I will lay on the isotope but can't verify. The shared effects are basically a totally rotten day. In two of them, I've had what I termed "flares" that required ramped up oxycodone to control. Can't remember what the third one was but it was a totally lost day. Never the same day or the same problems. But I'm sure they have all resulted from the isotope. And, as Jeff noted, Pluvicto is about the only thing that works after you've done all the others. Good luck and keep us posted.
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Some people have some major side effects from Pluvicto, most don’t. I have heard at least 5 people talk about their experience, In some cases they had to have more time between doses because of the side effects.
I saw a webinar where they discussed a person who lit up the Pet scan With metastasis from head to Legs. He had one Pluvicto Treatment and it almost cleared his pet scan, But his side effects were so bad that he could not take any more treatments
Be aware that it works really well for 33% of people OK for 33% of people and not at all for 33% of people.
If you have certain genetic issues, either hereditary or somatic, it can affect how well Pluvicto Works. You can ask for a somatic test before doing Pluvicto To find out if you’ve got Genetic changes Due to the cancer.
If you have BRCA2 or ATM It seems to work better. If you have RB1, PTEN or TP53 They are Pluvicto resistant. I don’t know if these are the only genetic changes that cause Pluvicto to work much better or more poorly.
Another person’s comments
My husband had six Pluvicto infusions over most of 2024 and had none of the severe side effects that some people experience. He had some fatigue, dry mouth from his saliva glands being affected by the treatment, and his appetite for food decreased in that most things just didn't appeal to him. His last Pluvicto infusion was in August 2024, and the only side effect remaining is dry mouth.