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Idiopathic Small Fiber Neuropathy Research

Neuropathy | Last Active: Aug 18, 2025 | Replies (155)

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Profile picture for jeffrapp @jeffrapp

Hi John, I like the first article you presented. It makes me think that a simple, harmless approach may have some scientific validity. Using moisturizing cream, and/or essential oils, is recommended by some for PN. Perhaps it may work by healing skin damaged by the enzyme mentioned in the article, even if only temporarily. I admit to being very lazy about doing this, and intend to do it more often. It couldn't hurt, and may allow me to get back my job as a leg model.

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Replies to "Hi John, I like the first article you presented. It makes me think that a simple,..."

Hi Jeff, My days of being a leg model are long gone 😂 but I do put a moisturizer on my feet and legs every night just to hopefully help with the possibility of the nerves getting better.

I tend to overlook total skin care too so good suggestion.

I also laughed at your leg model comment. We need a laugh reaction option! 🤣

Look up winsantor. They have stage 2 clinical trials of topical pirenzepine that has been shown to be effective. They are struggling to get funding to complete stage 3 trials.