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richardfrancine avatar

Has anyone tried Vyepti infusions for migraines?

Headache & Migraine | Last Active: Oct 17, 2025 | Replies (39)

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Profile picture for lzimm @lzimmerman

I am 62 years old and have suffered from migraines for 20 years. I used to get them 4 days/week and have tried every medication, Botox and other injections currently on the market as well as some non traditional ideas. Rizatriptan (Maxalt) did help a lot in stopping my migraines when they occurred. However, it did not reduce the amount migraines and at times I had rebound headaches. I now get Vyepti infusions quarterly and only experience one migraine/month. I still use the Rizatriptan as a rescue drug when I do have a migraine. This has been life changing for me.

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Replies to "I am 62 years old and have suffered from migraines for 20 years. I used to..."

Yes, I have a Vyepti infusion (300 mg) every 12 weeks. For a while, the infusions reduced the number of attacks I got but lately, their effectiveness seems to be waning and I’m getting more frequent attacks. I would label the infusions as somewhat effective and better than nothing. But my migraines are definitely still there. Worth a try bc everyone is different.