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← Return to Methotrexate side effects
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Polymyalgia Rheumatica (PMR) | Last Active: Sep 22 3:00pm | Replies (45)
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I requested the injection form of Mx for those very reasons. Though I dread poking myself each week, I've had zero side effects. It's been a worthwhile trade-off for me.
Side note: after two years of not being able to taper below 9mg pred, even after adding Mx, I started Tyenne (biologic similar for Actmera) very recently. It's too soon to really tell, but signs are very positive so far. I asked the rheumy about stopping Mx and she said she wants me to focus on dropping steroids first since they have much worse effects than Mx.
Replies to "I requested the injection form of Mx for those very reasons. Though I dread poking myself..."
Thank you for your comments. I had not considered the injection.
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MX will only have less worse effects than steroids if you don't get any of the bad side effects of MX. There are lots. It can severely impact on your bone marrow and that leads to all sorts of bad issues, with severe disruptions to blood cells, inflammation in spleen and pancreas, and escalating temperatures. Admittedly this type of toxicity which I experienced after two years is rare, but if the Mx is no longer helping reduce the steroids, there seems to be no point in taking that risk. Been off it for 8 weeks after an emergency stay in hospital and feeling so much better.