OH MY GOODNESS! THANK YOU for your amazing update. I am thrilled beyond measure that the coffee ketorolac combo has mitigated those horrendous unbearable hypnic/cluster headaches. I am so sorry I could not read this before. We moved my father in-law into hospice care Wednesday and have had challenges and been with him around the clock. Also was stricken with my usual "end of dose failure" of my CGRP injectable preventative, Ajovy (sickly daytime migraines) .

I am so so happy for you! Please ask your MD pronto--call them on Monday--ask whether or not you might need concomitant Protonix/pantoprozole to prevent GI bleeding (due to the Ketorolac and any day-time nonsteroidals you might be taking such as Motrin, naproxin, aspirin an many others). Ketorolac is only recommended for 5 days or fewer in a row. It, like Indomethacin/Indocin, can have serious side effects on the GI (gastric bleeding, ulcers and holes in stomach or intestine), kidney failure, heightened risk of heart attack, and others). Now that you feel better, the last thing you would want to do have uncontrolled GI bleeding or worse. Here is a link to more info: https://medlineplus.gov/druginfo/meds/a693001.html

Ketorolac, like Indomethacin (Indocin) also has a BLACK BOX Warning to to the risk of intestinal bleeding.

Please tell Dr. Sacco I said HELLO and appreciated her help back in 2005 and 2006. I hope and pray she can help you feel even better and treat your headaches more safely than daily Indocin. I wonder if she will recommend keeping Ketorolac in your regimen or trying an alternative. Please please keep me posted!! I hope you are well on your way to getting your life back!!!