1. < Digestive Health
Profile picture for mikejjb123

PPI use and side effects

Posted by mikejjb123 @mikejjb123, Sep 20, 2022

My doctor told me to take dexlansoprazole in the morning for chronic nausea when nothing else worked. Well, not so nauseas as before, but now have a bad acid taste in mouth all day long. Not seeing dr for another month. Any ideas or suggestions. Was taking pepcid twice a day but now only at night. Thanks.

Interested in more discussions like this? Go to the Digestive Health Support Group.

Profile picture for dawnsdc
dawnsdc | @dawnsdc | Aug 10 10:07am
In reply to @bosco17 "Ive been on 40mg of Pantoprzole for 4 weeks and my RBC count, Hemoglobin,Iron, Hematocrit have..." + (show)
Profile picture for bosco17 @bosco17

Ive been on 40mg of Pantoprzole for 4 weeks and my RBC count, Hemoglobin,Iron, Hematocrit have gone abnormal. Anyone else having these types problems?

Jump to this post

Has anyone done any investigation into ways to ensure enough nutrients are being absorbed while on PPI's? I have always been vigilant about healthy food intake, but being on PPI's indefinitely greatly concerns me. Thank you.

REPLY
2 replies
Profile picture for linh
linh | @linh | Aug 10 12:35pm
In reply to @gina97 "So, long story short, two weeks ago I took an antibiotic course + esomeprazole to treat..." + (show)
Profile picture for gina97 @gina97

So, long story short, two weeks ago I took an antibiotic course + esomeprazole to treat my H pylori infection. Throughout the ten days of treatment my digestion improved a lot, as before that I was dealing with severe delayed gastric emptying with food sitting in my stomach for as long as 8 hours. I was barely able to eat, cause I would get extremely full and bloated just after a few bites, throughout the day I would keep regurgitating food, constant acid reflux and the nausea was unbearable. It was a total nightmare that caused me to become severly underweight and malnourished. So during treatment all these symptoms had improved a lot and as soon as I finished the treatment, my digestion slowed down again so I started thinking what could be the cause of it and I realized that my digestion had improved on the same day I started taking PPIs which was a few days before starting the antibiotics. So I tried taking then again and guess what, digestion improved again. But this makes zero sense to me, because two years ago I tried taking PPIs and they made my digestion way worse which makes sense since that’s actually a known side effects of PPIs given that they suppress the acid needed to digest food. The only theory that I came up with is that since I have severe diffuse gastritis (diagnosed through endoscopy and biopsy) the PPIs might be calming down the inflammation and allowing the stomach to digest better and faster… does this make sense to anyone? Has anyone experience anything similar?

Jump to this post

I was on antibiotics for other health reasons, but relate to many of your symptoms (primarily due to a history GERD). As antibiotics are known to affect normal bacteria flora too (And my guess is G.I. preps do as well), I just assumed that my normal flora was undergoing rebalancing to some degree. I turned to seasoned acupuncturist for help with this, and have been feeling more like myself.

REPLY
Profile picture for missy245
missy245 | @missy245 | Aug 10 6:25pm
In reply to @dawnsdc "Has anyone done any investigation into ways to ensure enough nutrients are being absorbed while on..." + (show)
Profile picture for dawnsdc @dawnsdc

Has anyone done any investigation into ways to ensure enough nutrients are being absorbed while on PPI's? I have always been vigilant about healthy food intake, but being on PPI's indefinitely greatly concerns me. Thank you.

Jump to this post

I'm not sure there is much that will counteract the suppression of the acid environment in our stomach that is needed for proper breakdown and utilization of our food PPIs were never intended for long term use. They were to be used for acute situations such as ulcers. For long term use it is much safer to take H2 blockers like Zantac but even those should ideally not be used long term.
Has a physician prescribe PPI's for you?
I have been taking Histamine 2 blockers for 2 1/2 years for pre-cancerous cells in my stomach. My physician first prescribed PPIs and I told him I wouldn't take them, but agreed to the Histamine2 blockers (Zantac) . I don't feel I can take the risk of taking nothing. But I think, if people have less serious issues, it probably would be best to first try diet changes and something like Tums.

REPLY
Profile picture for baguette
baguette | @baguette | Aug 11 7:03pm
In reply to @dawnsdc "Has anyone done any investigation into ways to ensure enough nutrients are being absorbed while on..." + (show)
Profile picture for dawnsdc @dawnsdc

Has anyone done any investigation into ways to ensure enough nutrients are being absorbed while on PPI's? I have always been vigilant about healthy food intake, but being on PPI's indefinitely greatly concerns me. Thank you.

Jump to this post

Would blood tests for vitamins/minerals do the trick?

REPLY
1 reply
Profile picture for missy245
missy245 | @missy245 | Aug 12 4:27pm
In reply to @baguette "Would blood tests for vitamins/minerals do the trick?" + (show)
Profile picture for baguette @baguette

Would blood tests for vitamins/minerals do the trick?

Jump to this post

You could certainly monitor with blood tests, but then if you needed supplements, you then get into the how well would they be digested and absorbed.
What I have noticed after 21/2 years on an H2 blocker is that my finger nails are not as strong as they used to be. They chip really easily now when they never did before.

REPLY
View MoreView Less
Please sign in or register to post a reply.