I just got the results from a test that I think is a newer one, it's called Early Sjogren's Syndrome Profile. I have not tested positive for Sjogren's for 6 years, although I have some of the symptoms and a positive ANA. This test had 9 components that tested specific things related to the salivary and parotid proteins and other antibodies. I tested positive for 'SALIVARY PROTEIN 1 (SP 1) IGM ANTIBODIES'. Apparently it was developed because the older tests would only register positive after some fairly extensive damage has been done and the antibodies are high enough to detect. The hope is that they can find this sooner and prevent damage to the salivary and parotid. I have had and am currently having some serious ear problems, I had to have an eardrum replacement several years ago and am once again having severe retraction of the eardrum and inflammation of the mastoid. Sjogren's can damage the salivary glands and cause inflammation of the eustachian tube which will create middle and inner ear complications. Thank goodness that they continue to find new and more sensitive tests, after 6 years I am finally getting some diagnoses due to a couple of new tests; the second test is the CCP. I never test positive on the RF or CRP tests, but did on the CCP. Keep asking questions!