I began taking Tylenol and Claritin 2 days before. Continued the day of and 2 days after. The Tylenol was 650 mg. One Claritin (24 hr.) per day. I made sure that I drank at least 48 ounces of water each of those days, but tried to do more when I could. I can't tell you my numbers because we just moved and everything is packed up...sorry! Just be sure to drink 32 ounces of water the morning of the infusion before you have it. They will do ( or should do) a saline flush before and after the infusion. I think that's what they call it. Insist on a 45 minute infusion. They may not want to do it, but do not allow them to do it in 15 minutes or even 30. Personally, I think the shorter times and lack of preparation (water, Tylenol, Claritin) may be contributing to so many people having acute phase reactions. I noticed that one person said they didn't even have a fever. I didn't, either. You've got this!