← Return to Aromatase Inhibitors: How to choose and manage side effects?

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Hi! @tullynut:

Thank you so much for sharing this very valuable information regarding the impact of taking AI medication on the illness of dementia!

Could you please also share the link to this article, please? I am wondering when they did this research of comparing those ladies that were taking AI medications vs the ladies that did not take any AI medications, did they - by any chance - specify any particular aromatase inhibitors? For I am curious about whether taking different aromatase inhibitors makes any difference in regard to the impact on dementia? For those AI medications have different structures in them - even though their main function is the same...

Thanks again for helping us, comrade! Best wishes to all on this journey!

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Replies to "Hi! @tullynut: Thank you so much for sharing this very valuable information regarding the impact of..."

All I can tell you is that the article cited a study published in JAMA and was done by the University of Pittsburgh. I think it’s fairly recent and would suspect if you do a search on JAMA you may be able to find there. I have seen it cited a couple of times online. I used to live in Pittsburgh so I’m confident that studies done at the university of Pittsburgh are well run. Hope that helps.

Article: hormone therapy for breast cancer linked with lower dementia risk UPMC july 16, 2024

Hormone modulating therapy used for the treatment of breast. Cancer was associated with a 7% lower risk of developing Alzheimer’s disease and related dementias later in life according to a new study published today in JAMA network open.

Authors include: MODUGNO, CAI.

18,808 patients fitted criteria.

Search “hormone therapy for breast cancer linked with lower dementia risk “and you should be linked to the article with that title

I think this is the article she mentioned. As I search, there are quite a few articles pointing to opposite direction. Nothing is concrete about this finding, but we can always hope. The key is looking for credible websites, ethical statements, and conflict of interest statements.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2821165
https://pmc.ncbi.nlm.nih.gov/articles/PMC11803411/