Reclast infusion

Posted by eead @eead, May 20 11:12am

I had the Reclast infusion at the end of February 2025. Since then I have had great pain in different parts of my body. I have gone from being a very active person (walking, gardening, exercising, etc.) to being unable to do most things. The pain is especially bad at night in my lower extremities, causing me to have difficulty sleeping. The pain management doctor wants me to have a spinal epidural for narrowing of the spinal and foramanal canals because the pain in my back, buttocks, thighs, and legs is so bad. Could the Reclast be causing some of this pain? If so, is there any way to reverse the Reclast?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Profile picture for mlm56 @mlm56

I have had 3 annual Reclast infusion and have never had any side affects. However, neither my primary physician or periodontal surgeon (had implant in Feb) want to be the person to ok a 4th year of ReClaxt due to a possible disintegration of my jaw without an Endocrinologist ok.

Any suggestions or advice? Thanks

Jump to this post

May I ask why you want a fourth year when ReClast stays in the bodyfor years and even 1 infusion may provide protection for up to 10 years?

REPLY

Thanks for commenting. The first 2 years there was no improvement on my Dex score but my 3rd year I finally had improvement. I was advised the ReClast doesn’t stay in one’s system that long (10 years). Because I have ‘plates and screws’ as a result of broken bones both vertically and horizontally, I want to improve the density but not have the negative outcomes.

This is a genetic thing for me and I am a very active person and want to continue on without another broken bone this year. Thanks for your insight.

REPLY
Profile picture for mwendt54 @mwendt54

@ dannyandebbie

I have rheumatoid arthritis and am in daily pain. My endocrinologist wants me to have Reclast for my osteoporosis. I’m terrified to take it. I can’t take any of the oral meds due to GERD. I’m thinking of just doing nothing as far as medication goes. Has anyone else not done medication for osteoporosis?

Jump to this post

I’m just new to this group… but I just had the reclast infusion.. I wouldn’t advice my worse enemy to get it… It’s been 10 days and I’ve been literally in bed with such pain, I thought I was having a flare up with my RA so I took my methprednisone pack and it did nothing .. because it wasn’t my RA …
My general practitioner adviced me not to get it again!
I would love to know if you have it and if the side effects are the same.. I pray that they aren’t!

REPLY
Profile picture for annms01 @annms01

I’m just new to this group… but I just had the reclast infusion.. I wouldn’t advice my worse enemy to get it… It’s been 10 days and I’ve been literally in bed with such pain, I thought I was having a flare up with my RA so I took my methprednisone pack and it did nothing .. because it wasn’t my RA …
My general practitioner adviced me not to get it again!
I would love to know if you have it and if the side effects are the same.. I pray that they aren’t!

Jump to this post

I’m sorry to hear you’re feeling so awful. No I have not had the Reclast infusion yet. I think I’m going to wait until my follow up DEXA scan in February, see how much if any my numbers have changed and reevaluate. I’ve heard terrible things about how sick many become after Reclast and I’m not sure it’s worth the risk. Thank you for sharing your experience.

REPLY
Profile picture for nraeoregon @nraeoregon

I had my first and last reclast infusion last August. I want to find if others had the same reaction to the treatment as I did. 5 days after the infusion I developed terrible swelling in my joints, and could barely walk. I was in so much pain. The swelling only relented after a several days on a very powerful prescription anti-inflammatory med. I am still in pain daily, mostly in my hips and lower back. I have gained weight and am less inclined to exercise because it just hurts more. Has anyone else had this experience?

Jump to this post

Had my Reclast early July 2025. Joint pain started four days later and on the sixth could not walk for an hour and a half; a lot of swelling in both knees and felt like lead weights had been put on. My rheumatologist said I was on the 3 percent that gets adverse effects and said it could take two weeks to two months to go away. Weird thing is that in a week I was fine! Been hiking this month and all is fine!

REPLY
Profile picture for louiemeyers @louiemeyers

Had my Reclast early July 2025. Joint pain started four days later and on the sixth could not walk for an hour and a half; a lot of swelling in both knees and felt like lead weights had been put on. My rheumatologist said I was on the 3 percent that gets adverse effects and said it could take two weeks to two months to go away. Weird thing is that in a week I was fine! Been hiking this month and all is fine!

Jump to this post

That is great. I still have considerably more joint and arthritic pain a year later. Not sure if this is normal aging or something caused by the Reclast infusion. Plus now I see from a poster on this discussion that her oral surgeon would not do dental implants for her since she had used Reclast. I regret having agreed to the infusion. I'm glad your pain was brief.

REPLY
Profile picture for louiemeyers @louiemeyers

Had my Reclast early July 2025. Joint pain started four days later and on the sixth could not walk for an hour and a half; a lot of swelling in both knees and felt like lead weights had been put on. My rheumatologist said I was on the 3 percent that gets adverse effects and said it could take two weeks to two months to go away. Weird thing is that in a week I was fine! Been hiking this month and all is fine!

Jump to this post

I’m so glad yours just lasted a week… you know the pain..
I can’t wait till I’m there it’s going to be 2 weeks tomorrow.. still can’t lift my arms .. I don’t want get discouraged!
So happy for you that you are back to hiking etc..I’m so happy for you!
It makes us realize how blessed and grateful we are for a healthy body when things like this happen!
God bless !!!

REPLY

If someone read only the comments here, they'd conclude that there is a 100% chance of bad side effects with Reclast. That is not the case. That isn't to dismiss the people who have had issues, not at all, but the majority do NOT have a problem.

REPLY

Agreed. The only people who reach out are people who HAVE side effects. People should speak with their doctors and there are ways to avoid the possibility of side effects by slow infusions and taking NSAIDs before the infusion. I think its only 10% of ONE PERCENT who have side effects and it goes down much further on the second. The people who have side effects are possibly the ones who really BENEFIT from the meds.

REPLY
Profile picture for mwendt54 @mwendt54

I’m sorry to hear you’re feeling so awful. No I have not had the Reclast infusion yet. I think I’m going to wait until my follow up DEXA scan in February, see how much if any my numbers have changed and reevaluate. I’ve heard terrible things about how sick many become after Reclast and I’m not sure it’s worth the risk. Thank you for sharing your experience.

Jump to this post

I had the Zometa which is the same as reclast. I thought I did pretty well until about 4 days later. I felt so sick and achy. I had some regular labs ordered at the same time and found that my kidney function had dropped dramatically. I am due another in 6 months, but I don’t think I could survive that again. It was terrible.

REPLY
Please sign in or register to post a reply.