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Cytology: High-grade urothelial carcinoma to atypical sqamous cells
Bladder Cancer | Last Active: Aug 8, 2025 | Replies (10)Comment receiving replies
Hello Fran,
Thank you for following up on my post and your wishes! I am sorry that you are in a similar situation as my wife.
I have news to report: My wife did two new cytology tests since my post. The first gave "ATYPICAL UROTHELIAL CELLS" and the second, "NEGATIVE FOR HIGH-GRADE UROTHELIAL CARCINOMA". It seems a good news, but it is uncertain. The urologist said that this change in findings happens but it is not common. A new cytology test will be done this month and I will inform you the results.
The cytoscopy procedures didn't show abnormalities that prompted biopsies. If the next cytology test comes positive, it is possible that random biopsy samples will be taken.
There is a condition called "carcinoma in-situ" that is difficult to spot in a cystoscopy. But there is a procedure, "Blue Light Cytoscopy", that allows to see this type of carcinoma. Unfortunately, there is no such equipment at our local hospitals and the urologist didn't refer my wife to another location. I have literature on this procedure that I can share with you and I may find out which hospitals at your location have the equipment.
Regards and my best wishes,
Hector
Replies to "Hello Fran, Thank you for following up on my post and your wishes! I am sorry..."
Pardon me Hector & Fran, my name is Robert and I just came across your conversation. Talk about coincidence! I have an appointment at the Cleveland Clinic on Monday with Dr Amanda Nizam, who happens to be a co- author for the UNITE study group. Her input revolves around UNITE which is an acronym for Urothelial
cancer
Network
to
Investigate
Therapeutic
Experiences
Ergo UNITE study group. Perhaps, (if you wish) I would be glad to ask her about the situation y’all are finding yourselves in and maybe shed some light instead of no answers? It just sounds like you’re working your tails off to find out about some high grade urothelial carcinoma which I’d like to help and maybe get y’all some answers from the horses mouth? Robert or as known here as Chebo54
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Dear Hector,
Thank you so much for the information. I hope all future test for your wife are negative.
I look forward to hearing back from you. I will share anything I learn with you.
Best regards,
Fran