From what I read here I don't understand why more doctors don't prescribe LD Naltrexone for pain. Do you suppose it is more profitable for them to prescribe very expensive new drugs like Cymbalta? I have tried several of the new "wonder drugs" and have had adverse reactions to all of them. I won't take any drug that ha been on the market less than 10 years. I used to take Midrin for headaches, including migraines, but it was taken off the market because there had never been clinical trials that proved it was effective although millions of people had taken it successfully for years. Shortly thereafter, all these new migraine drugs hit the market. Every person is different and may have different reactions to a drug. My husband has no problem with 2 drugs that cause me to have severe reactions.