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jshaw1663 avatar

Rheumatoid arthritis.

Autoimmune Diseases | Last Active: 8 hours ago | Replies (66)

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Correct about ascorbic acid - but methotrexate can have other serious side effects. I couldn’t take it at the beginning .. liver. Now, decades later I could ( to better support Biological Orencia ) for over a year - then it hit the liver again . So off of it . Altria’s another dressed modifier but it gave me such bad ‘fog brain’ I stopped. At a loss now - so is RA Dr! 😢

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Replies to "Correct about ascorbic acid - but methotrexate can have other serious side effects. I couldn’t take..."

I think you meant folic not ascorbic acid? It’s true, MTX can have some undesirable side effects for some, but for many they adapt well to it and it can prevent the disease progression and damage that RA does.

Has your doctor mentioned low-dose Naltrexone as an option? (Not to be confused with Naltrexone used to treat alcohol and drug abuse - I always have to clarify that as we’re going over my drug list with a new doctor!) It’s another possibility and often tolerated well. Many start at 4.5mg. It’s a drug that you’ll have to get at a compounding pharmacy. I think it’s helping; others swear by it. I believe if you search within the Mayo forums, you’ll find other posts with additional info 🙂
https://pmc.ncbi.nlm.nih.gov/articles/PMC3962576/