I’m not sure what mast cell activation syndrome is, but my daughter has an autoimmune condition as well and has multiple anaphylactic allergies - she is also allergic to her own sweat so has to be careful not to break out in a sweat which can trigger hives (her hives can be triggered by anxiety and stress too), which in turn triggers anaphylaxis. She cannot even be in the same room with latex (e.g., balloons), strawberries, kiwis or pineapples. On the whole she literally walks an allergy landmine. She needs to carry two Epi Pens with her at all times.

She has been taking Xolair injections once a month in a clinic setting for about four years now. It has helped with her hives. Also, she was allergic to almonds and coconut among her long list of allergies, but after a few Xolair injections she has been able to eat first almonds, and then coconut (she was given small portions at the clinic, under observation). She still is allergic to other tree nuts. It is hoped that in time she will be able to tolerate other items on her long list.

Xolair injections are a work in progress for her, but they definitely are helping. Fortunately for her, her health plan from her workplace covers the injections.