Hello! I was on methotrexate up to 20 mg for a year. I didn't have much of a response to it. I used Mega folinic from Source Naturals instead of the prescribed folate because it is more bioavalable.
I was on methotrexate and Humira for about 6 month, with barely measurable difference.
I'm off meds since January, until 2 weeks ago, when I started low dose naltrexone at 4.5 mg. I'm hoping it will help with fatigue and inflammation.
I had low-grade nausea from methotrexate. I read that taking dextromethorphan along with it can help with side effects.
My liver enzymes were checked every 3 months, and didn't rise until the last month I was on methotrexate.
This is just my experience. Many people have experienced success with these treatments, and I hope your experience is successful!