Diagnosed 7/1/2021 with stage 2/3 ESCC and went to MDA in Houston for chemo and proton therapy treatments which successfully eradicated the tumor and cancer in involved lymph nodes. Furloughed 7 weeks to recover prior to return to Houston for surgery. Upon return PET scan revealed cancer returned in 2 new locations, changing my status to 4B metastatic and not eligible for surgery. Returned home for new round of chemo with immunotherapy (Opdivo). I also signed up for periodic Signatera blood biopsies. At the end of chemo treatment in 3/2022 no evidence of cancer and I stayed on Opdivo for about an additional 26 months. I have been in remission for 3 years 5 months (not that I'm counting). My Signatera score has been "0" since 3/22 which means there is no evidence of my tumor's DNA in my blood. In a few weeks I will be 75 and life is good though my doctors remain vigilant since my cancer is not considered curable. Good outcomes do happen.