Just took a look at this base, and I can see why you might be interested. We've got an adjustable bed from a different brand that doesn't vibrate, and I'll offer these thoughts:
-- I personally find tempur pedic and similar mattresses problematic. I sleep hot, and they make me even hotter. There are post-market products that you can put on top of a mattress to cool it down, but I have no idea how well they would work on one of these when the bed has been bent in the middle.
-- If you normally sleep in the same room/bed, consider a split king or split CA king instead of a queen or king. Ours is a split, and I'm so glad we went that way. It totally keeps us from having to negotiate a setting that works for both of us at the same time, which realistically would have been impossible.
-- Making the bed in a split is a bit of a pain, especially if you have back issues; lots of reaching and bending to put on the bottom sheet where the two mattresses butt against each other in the middle. We finally found these: https://quickzip.com/. I normally don't endorse specific products, but the fitted bottom sheet solution here is great! Basically, you pull the bottom sheet into place the first time as you would normally. After that, you just unzip the top to wash it, and zip the top back into place. I believe there's a video that shows how to do it. It's not in the least difficult, but it is also not intuitive.
-- Our bed required professional installation, and the frame is really, really heavy. We're going to need people who are a lot stronger than we are to move it, if we ever need to do so. You really want to position it correctly the first time if yours is too heavy for you to move yourselves.
-- We needed two electric outlets for the split, since they are entirely independent motors and the cords were not terribly long.