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I have recently switched from Actemra to Tyenne due to insurance.
Polymyalgia Rheumatica (PMR) | Last Active: 14 hours ago | Replies (7)Comment receiving replies
The active ingredient (tocilizumab) is similar for both, except the "AAZG" in tocilizumab in Tyenne is apparently Aluminum zirconium trichlorohydrex glycine, an ingredient commonly used in anti-perspirants to block sweat pores. What purpose does it have in Tyenne? No idea. The other inactive ingredients are also different. I wonder if you're having a reaction to one of the new ingredients? I'd also be interested to know how others who have switched brands are doing.
TYENNE
Active ingredient: tocilizumab-aazg.
Inactive ingredients of Tyenne: arginine, histidine, hydrochloric acid, lactic acid, polysorbate 80, sodium chloride, sodium hydroxide and water for injection.
ACTEMRA
Active ingredient: tocilizumab.
Inactive ingredients of Actemra: disodium phosphate dodecahydrate/sodium dihydrogen phosphate dihydrate buffered solution, polysorbate 80, sucrose, and water for injection.
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@megz I absolutely hate taking Tyenne. Had to switch to it from Actemera due to coverage. Experiencing horrible side effects. Dry mouth, mucus build up in head and throat, nose crust build up, fatigue, swelling in hands and feet, sore throat, and change in eye white color.