I am so sorry you are dealing with these horrid headaches. They are wretched and defeating. Are you seeing a Neurologist now, and if yes, are they a Headache specialist? Have you been to the ER to manage dehydration from vomiting/diarrhea or intractable pain? I hope and pray your physician is able to isolate a cause, or experiment with a med to treat a potential inflammatory type headache. Please keep a journal as to what time of night they occur, how many times per night, and if the headaches are all the same or progressively worse as the night goes on. The residual the day after also left me with intense nausea and dislike of food odors. Antinausea patches helped calmed the nausea. The night-time headache never responded one iota to any of my migraine treatments. The headache specialist, Dr. Sara E. Sacco I saw in Charlotte is apparently practicing at Carolina's Headache Clinic in nearby Matthews, NC. I looked up her health grade 20 years later and her ratings are still high. I hope she is taking new patients and can help you. If I were in your situation I would definitely seek a headache specialist and beg to be soon ASAP. If your insurance will cover your referral to Mayo clinic you might consider an appointment with specialists who have seen and treated everything. Bring records of your history, your journal and every headache medicine (or other non drug treatment) you have tried and ask if they feel you would benefit from an anti-inflammatory treatment or something else that has been beneficial in treating hypnic headaches (google Hypnic headaches and look at recent Research and analysis of the headache type. Please keep us posted as to what you decide to do, and results of your appointments and treatments. I pray you get some much needed relief from the onslaught of severe pain that is crippling and makes us afraid of going to sleep. Yet the pain is so exhausting as is the resultant dehydration, loss of sleep, and a dire feeling of hopelessness. Feel free to send me a private message via this site if you prefer to talk privately.

I see that this topic goes back several years. I have posted in other threads about migraines. I’m 76 and have had headaches since my mid 30s. They have changed over the years but imitrex has always helped.
I recently developed morning headaches that occur while sleeping. I think they are hypnic but I’ve been told by the neurology NP I’ve seen at Emory that they are rebound headaches from imitrex.
I will be seeing Dr. Charles Gordon in Charlotte in October. He is an internist who specializes in migraines and was recommended.
Like many of you, I’ve been through many meds and many opinions about causes and cures. Unless you experience headaches you don’t understand them. I was told that Dr. Gordon understands. 🤞🏻🤞🏻🤞🏻