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Is there ever a cure for stage 4?

Prostate Cancer | Last Active: Aug 6 7:30am | Replies (22)

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Profile picture for jeff Marchi @jeffmarc

As you know if your PSA starts to rise, even though you’re on ADT, you have become castrate resistant.

The thing is, you don’t give any numbers. If your PSA went from .001 to .003 well, that’s not really a much of a PSA rise and it may go down as much the next time. If you have a significant rise, then you will need to get on an ARSI (Zytiga or a lutamide).

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Replies to "As you know if your PSA starts to rise, even though you’re on ADT, you have..."

Technically I’m not sure that I’m castrate resistant.

The ominous fact is that my PSA went from undetectable to 0.05 while I was on a full course of DEGARELIX.

My next reading of 0.09 occurred 46 days after my last dose of DEGARELIX. The half-life of that drug is 28 days so more than half of the drug was out of my system by the day of that PSA reading.

I may be splitting hairs, but because my oncologist didn’t say maybe we should go two more months two more doses because that move from undetectable to 0.05 hints a at castrate resistance, but does not prove it.

My total time on degarelix has been 24 months, but in two very distinct one year periods. My first stint also included about six months of Lupron instead.

Also, my last stint that just ended included Diarlutimude, up until early June. So I’d be a little surprised to find that I was castrate resistant after only 24 elapsed months total and with the last six months with no prostate.

If you detect some grasping for straws, here you are correct

* I’m getting a little exasperated by the iPhone, not understanding the names of any prostate cancer drugs. So please forgive all caps and egregious misspellings of various prostate cancer drugs.

My phone keeps interpreting “DEGARELIX” as “the garlic”, but rest assured, I am not yet trying any crockpot home remedies.