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Osteoporosis & Bone Health | Last Active: Apr 11 10:47am | Replies (21)
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lynn59, partly. We tend to measure the value of the pharmaceuticals in terms of bone density. Even the new TBS software measures density, but attempts to measure it in trabecular bone. Density isn't the only property of bone strength, it is the easiest to recognize with imaging.
And like Prolia, Evenity is fast.
Partly, though, it is Amgen's intense advertising campaign, directed our way, but mainly targeting and capturing our physicians, despite the black box warning for cardiac issues. "Plan Prolia as her next step after Evenity." There is speaker income and study funding for some. The endocrinologist I see proudly told me that he has been offered a speakership.
Both of these medication add layers of unarticulated bone to the outside of bone, where bone has never been before. It's called modeled bone because it prevents the removal of fissured, brittle bone.
Many women my age have very brittle bone from years of bisphosphonate use, and if a person is on the verge of fracture, these drugs could be the best choice.
The medications that build the strongest most integrated bone called remodeled bone are Forteo and Tymlos. Remodeling removes damaged bone, replaces that bone with articulated bone and restores lost trabecular bone.