Hello @lp0211, Welcome to Connect. I'm sorry to hear that your husband has not been able to find something to help with his increasing painful neuropathy symptoms. I only have numbness with mine which is aggravating enough but nothing compared to what your husband is dealing with. He's not alone with having trouble finding something that helps. It's a journey for most of us and thank you for being his advocate and helping him navigate through the maze of treatments.

What has helped me since joining Connect is learning as much as I can about my condition and the different treatments that are available that might offer some relief. There are many discussions in the Neuropathy Support Group. You might find it helpful to scan through the list of discussions to find other relevant symptoms and topics where you can learn what others have shared. Here's a list of the discussions in the Neuropathy Support Group - https://connect.mayoclinic.org/group/neuropathy/.

The Foundation for Peripheral Neuropathy is also a great source for learning more - https://www.foundationforpn.org/. They also have a YouTube channel where they keep all of their previous webinars on neuropathy topics. Here's a search of their YouTube channel listing webinars for managing pain - https://www.youtube.com/@foundationforperipheralneu4122/search?query=managing%20pain. Here is a list of Pain Management & Treatments for PN - https://www.foundationforpn.org/treatments/.

What is his most difficult symptom to manage?