I started AIs in Dec 2024. First was Letrozole--gave me terrible tinnitus, then Exemestane, again terrible tinnitus. Med. Onco. suggested taking Exemestane every other day, but that didn't help much. Switched to Anastrozole in March 2025. No problems at all. I never tried Taxomifen. I have no idea why I got along with Anastrozle, but not with the other two. Also there's Fulvestrant, but it's injectable (not a pill)--never tried it.

Also, Anastrozole seems to disturb my sleep, so I take it in the morning. I also take Kisqali (ribociclib--not an AI, but a CDK4/6 inhibitor because I have a fairly aggressive cancer) which seems to make me tired, so I take it at night.

My advice: don't give up on AIs until you've tried them all. Also see if morning dosing or night works better for you.