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Prostate Cancer | Last Active: Aug 6, 2025 | Replies (15)

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Profile picture for Jeff Marchi @jeffmarc

The fact that only 5% of your Gleason 3+4 was a pattern 4 is something that usually means you can go on active surveillance.

Yes, PNI can be an issue, but with such a low Gleason score and low pattern 4 percentage it again doesn’t demand immediate treatment. Prostate cancer is very slow growing, You should have plenty of time to make decisions on what treatment you want

It sure would be interesting to know what the PIRAD score Was for the tumor found in your prostate when you had an MRI. Was the PIRAD score a four or five, That shows there’s a possibility you have metastasis.

You shouldn’t need your doctor to give you a referral to get a second opinion. You can just contact a center of excellence or find a GU Oncologist. With your PSA and biopsy information, the doctors would have no problem giving you their thoughts on your treatment.

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Replies to "The fact that only 5% of your Gleason 3+4 was a pattern 4 is something that..."

My PIRAD score was "PI-RADS v2.1 score: 1" Which is exactly the same as it was in 2023. Its weird to me that my biopsies come up with cancer 3 times in a row and the MRI is clear, PIRAD score 1.

Whats your opinion on my .6 Decipher score being in the high risk zone? It even says on the test results print out: "These patients may not be ideal for active surveillance. These patients many benefit from treatment with definitive therapy."