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Replies to ""Prostatic adenocarcinoma, Gleason score 3+4=7 (grade group 2, pattern 4=5%), involving 1 of 1 core (5..."
Prostate Cancer | Last Active: Aug 6, 2025 | Replies (15)
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"Prostatic adenocarcinoma, Gleason score 3+4=7 (grade group 2, pattern 4=5%), involving 1 of 1 core (5 mm, 30%)"
I read that PNI indicates a pathway for cancer to spread out of the gland.
When we just had the biopsy report more active surveillance seemed like the way to go but then the .6 Decipher score muddied the waters. That indicates I am on the very high end of intermediate risk aka low end of high risk.
Replies to ""Prostatic adenocarcinoma, Gleason score 3+4=7 (grade group 2, pattern 4=5%), involving 1 of 1 core (5..."
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The fact that only 5% of your Gleason 3+4 was a pattern 4 is something that usually means you can go on active surveillance.
Yes, PNI can be an issue, but with such a low Gleason score and low pattern 4 percentage it again doesn’t demand immediate treatment. Prostate cancer is very slow growing, You should have plenty of time to make decisions on what treatment you want
It sure would be interesting to know what the PIRAD score Was for the tumor found in your prostate when you had an MRI. Was the PIRAD score a four or five, That shows there’s a possibility you have metastasis.
You shouldn’t need your doctor to give you a referral to get a second opinion. You can just contact a center of excellence or find a GU Oncologist. With your PSA and biopsy information, the doctors would have no problem giving you their thoughts on your treatment.