There are two small studies supporting using Evenity beyond a year and or repeating Evenity. My doctor has a small number of patients doing that and I intend to do that also after a year or so off of Evenity. I'm using monthly Risedronate in the interim. Insurance and money are issues unfortunately, but I hope to manage that somehow. My doc also suggested just using it for 6 months next time saying there was a Korean study that showed that you got most of the results from Evenity in 6 months. I intend to do whatever I have to do to have another round and get more gains in density.
As anecdotal evidence for Evenity I took a wrong turn in the dark recently and fell wildly down our basement stairs. I wrenched my foot and knee but broke nothing. That was quite an experience. Of course I don't know for sure what would have happened if my spine still had vertebra lower that -4.0, but I'm definitely glad I had all the density improvements from Evenity before I took that tumble.
BTW, I participated in that Inspire discussion that @19kcm56 mentioned. I'll post what I said there here:
"I found two relevant articles. In one they did two years of Evenity consecutively and in one they did a year of Evenity, then a gap of nothing and then another year of Evenity. There are other things going on in both these studies so you have to find the particulars of interest to you but both are highly relevant and encouraging.
In the first study there was continued benefit for the second year even though everyone says you can only take it for one year. The benefits did slow down but did not stop. No extra safety concerns found for second year.
In the second study more relevant to your situation the second year of Evenity following a 1 year gap was almost exactly as effective as the first. That one says no new safety concerns in second year.
The two years consecutive study:
https://pubmed.ncbi.nlm.nih.gov/29694685/
The 1 year, gap and then another years study:
https://link.springer.com/article/10.1007/s00198-019-05146-9
"
Best of luck to you
The one study compares people on Prolia after Evenity, then back on Evenity, and their gains were minor (around 2.3%). Since I am on Prolia now, if I had to pay the outrageous cost of Evenity again ($450 co pay per monthly injections) I’m not sure it would be worth it for that small of a gain. Still worth mentioning to my doctor.