My comment is directed to anyone living with chronic pain. I recently read a report in the Journal of the American Medical Association often referred to as JAMA. referencing the treatment of Chronic Pain. In this Journal it is reported that the use of a compounded drug called NALTREXONE used in low dose amount can relieve chronic pain in people! This a new discovery folks!! Also when used at a low dose (4,5 mg) there are relatively no side effects! It is also non-addictive! After reading the article I called and made a appointment with a pain specialist. He advised me that this drug has previously been used to treat patients who were coming off of drugs and it was only recently found that it relieves chronic pain. He said it's the best finding since he has been practicing medicine! My orthopedic doctor was totally unaware of the JAMA report and had never heard of NALTREXONE being used to treat pain. I encourage everyone in pain to bring this information to the attention of your treating physician. NALTREXONE is a compounded drug so it is not available at your local drug store. It is made by Compounding (Apothecary) Pharmacy. I hope this new information is helpful in your journey to relieve chronic pain. It sure has been a game changer for me.