I have suffered for many years with loose bowels and explosive bowels. I finally found a doctor that was able to help me. He prescribed 2 medications that have worked like a miracle. One is Diphenoxylate/Atropine and the second medication is Colestipol. It took a few months to really get it under control. Both medications are expensive even with Medicare Anthym Blue Cross. I have gotten to the point that I know how much I need to take to work 99% of the time. I'm so thankful for these two medications. There are breakthroughs maybe one or two days a month. That I can handle compared to multiple times every day.