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Osteoporosis and Dental Work

Osteoporosis & Bone Health | Last Active: Aug 11 1:16pm | Replies (22)

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I am in a state of panic as I never was informed about rebound drugs and dental work....After 2 yrs of prolia, I went from osteoporosis to osteopenia. Dr wants me to start Reclast but my dentist says I would have to wait a full yr if I had dental issue. Why do they get you off Prolia if it's working? Are there side effects or risks of taking Prolia for longer than 2 years? And how long does one remain on Reclast?

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Replies to "I am in a state of panic as I never was informed about rebound drugs and..."

jan12345678, Prolia is the rebound drug. Reclast is to protect you during the rebound period from Prolia. Does your dentist know you are on Prolia now, because Prolia has a greater risk for bone death with dental work than Reclast. It isn't just rebound that creates the risk from Prolia. It is the way both of these drugs work. They stop the cells that clear away older fissured bone. And that stops the cells that come in afterward to build new bone. So you end up with bones that are brittle and without an adequate blood supply. Prolia's mechanism collects the cells that remove damaged bone in their final stage of development. When you stop the drug, these cells finish developing quickly and engulf your bones in an acidic bath, often resulting in multiple fractures. Reclast prevents these osteoclast cells from attaching to the bone and causes them to self destruct.
Currently Reclast is the only medication that can safely make the transition away from Prolia.
Invasive surgeries--root canals or extractions create the risk. Cleanings and fillings are not a problem.
Prolia adds new bone very quickly to the outside of the existing bone. If a patient were at imminent risk of fracture or if they had cancer metastasized to the bone, Prolia would be a good consideration. But it takes that bone back and even more than it has given rapidly, when you stop the drug.
I suspect anyone knowing this about Prolia would never take it. Your doctor is showing you the proper escape route. It will very likely be successful.